Job Description

Research Associate I – In Vivo Electrophysiology & Behavior

The mission of the AllenInstitute is to understand the principles that govern life and to advance health. Our creative and multi-dimensional teams focus on answering some of the biggest questions in bioscience. We accelerate foundational research, catalyze bold ideas, develop tools and models, and openly share our science to make a broad, transformational impact on the world.

The mission of the Allen Institute for Neural Dynamics is focused on fundamental discoveries in systems neuroscience. We are interested in how the brain builds our understanding of the complex world to guide the flexible behaviors that address our biological needs. The answers will be in terms of defined neuron types and circuits interacting across the whole brain and body. We will develop next-generation methods and theories and employ a team-based approach to discovery in neuroscience. Knowledge, data, models, and tools will be widely shared to support the development of therapies for brain disorders.

We are seeking a Research Associate to contribute to a set of projects to record the activity of thousands of neurons distributed across many brain regions in parallel. The ideal candidate will be team-oriented, have knowledge in neuroscience and behavior, and display a strong interest in studying brain-wide circuits during behavior. This position will leverage state-of-the-art electrophysiological methods, such as Neuropixels probes, as well as molecular and transgenic resources. The goal is to record simultaneously from many anatomically connected regions while mice are engaged in a variety of cognitive tasks. The Research Associate will work alongside a diverse team of Scientists, Technicians, Engineers, and Investigators, and so collaboration and communication skills are key.

At the Allen Institute, we believe that science is for everyone – and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.

We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

Essential Functions

• Collect in vivo electrophysiological, optogenetics, and/or optical physiological data from mouse cortex using cutting-edge recording systems
• Train mice to perform various foraging behavioral tasks
• Participate in lab maintenance and weekly tasks
• Carry out analyses to assess overall data quality and use this information to update and refine experimental protocols
• Use histological techniques to identify probe recording location

*Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management’s assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.*

Required Education and Experience

• Bachelor’s degree in neuroscience or a related field

Preferred Education and Experience

• 2 years of experience in a research lab
• Experience working with mice greatly preferred
• Practical experience in in vivo electrophysiology and/or mouse behavior
• Strong scientific communication skills (written and oral)
• Ability to work in a team-based environment
• Experience with rodent surgeries

Work Environment

• Laboratory environment - possible chemical, biological, or other hazardous substances exposure Possible exposure to BioSafety Level 2 organisms, such as recombinant viruses This may include wearing personnel protective equipment (PPE)

Animal Care Services

• Exposure to and handling of laboratory animals required
• Pre and post-operative care for mice
• Administration of compounds to mice (iv, ip, sc, po, im, ro, icv)
• Perform health assessments of mice
• Perform euthanasia and tissue collections

Physical Demands

• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
• Stooping, bending, crouching
• Reaching, or climbing ladders

Position Type/Expected Hours of Work

• This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis.

Additional Eligibility Qualifications

• All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on your health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Annualized Salary Range

• $54,250 - $66,450*

* Final salary depends on the required education for the role, experience, level of skills relevant to the role, and work location, where applicable.

Benefits

• Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute’s Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute’s 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide. Details on the Allen Institute’s benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

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